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Whilst tirzepatide's mechanism helps mitigate these rises through enhanced insulin secretion and delayed gastric emptying, consistently high sugar intake may prevent achievement of optimal HbA1c targets

Similarly, liraglutide monotherapy for 3 months significantly reduced EAT thickness in obese T2DM patients, and this reduction was positively correlated with decreases in BMI (163)

[DOI] [PMC free article] [PubMed] [Google Scholar] 165.Davies JS

While some users experienced mild side effects, they were reported to be temporary and were outweighed by the benefits

Genetic variations in the GLP-1 receptor gene (GLP1R) and related metabolic pathways can influence medication efficacy, side effect tolerance, and weight loss magnitude

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