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Moreover, dihydroartemisinin may decrease the expression levels of the key G0/G1 regulators, CDK2/4, and cyclin E1 through the mTOR/HIF-1 signaling, thereby inducing A549 cell cycle blockade and alleviating gefitinib resistance (Hu et al., 2023
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doi: 10.1080/19490976.2025.2517821 132 AsnicarFBerrySEValdesAMNguyenLHPiccinnoGDrewDAet al
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