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In heart failure, expression of BCAA metabolic enzymes is regulated by transforming growth factor--activated kinase 1 (TAK1) and p38 MAPK signaling pathways, with downregulation of the transcription factor KLF15 leading to systemic decreased expression of BCAA metabolic enzymes (91)

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Du ToitGRobertsGSayrePHBahnsonHTRadulovicSSantosAFet alRandomized trial of peanut consumption in infants at risk for peanut allergy