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Disc herniation involves both mechanical factors (the displaced disc material) and biochemical factors (inflammation)

A separate ligament study (Cerovecki et al., 2010, Journal of Orthopaedic Research ) reported improved medial collateral ligament healing in rats over 90 days post-transection, with effective dosing observed across intraperitoneal, oral, and topical routes

Thus, GSH participates in cysteine-induced signaling via its degradation and ability to replenish cysteine pool in HepG2 cells