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When residues L43, W53, and F54 were substituted with alanine, the inhibitory ability was significantly reduced, indicating that these hydrophobic residues were essential for FOXO4 FHD binding (Table 1)

The Am J of Pathol 165, 1719730

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A 2016 study involving hospitalized people found that the participants with high B12 levels needed longer hospital stays and had a higher chance of dying

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