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Semaglutide has demonstrated the capacity to decrease both recurrent alcohol consumption and total alcohol intake in rats by over 50% (Aranas et al., 2023)

Lipidation of peptide molecules enables GLP-1 to attach to albumin, which can ultimately lengthen its duration in circulation

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Within the small intestine, pancreatic enzymes, including trypsin, chymotrypsin, elastase, and carboxy-/aminopeptidases, continue proteolysis, which reduces peptides to fragments or amino acids