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Ethics statement The studies involving human participants were reviewed and approved by CAMH Research Ethics Board

LEADER compared liraglutide to placebo in 9340 patients with T2DM and known CV disease or CV risk factors only [16]

PMC 4572142

GLP-1 appears to attenuate the process of neuroinflammation and protects neurons and glia under oxidative stress conditions in the depressive brain

Mechanism of Action Melanogenesis Stimulation: Activation of MC1R stimulates the synthesis and release of eumelanin (the protective, dark pigment, typically black/brown), as opposed to pheomelanin (the red/yellow pigment)