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The anorexigenic effect is caused by the hormone binding centrally to the MC4R and peripherally to the MC2R

Further it is known that the gut microbiome is involved in the synthesis of neurotransmitters such as glutamate, serotonin, noradrenaline, dopamine and gamma aminobutyric acid (GABA) and their functions and bioavailability both in the central nervous system and in the periphery

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These effects have positioned AOD 9604 as an important research tool for adipose tissue biology and metabolic investigation

They also say 20 million Americans have some type of thyroid disease

Available from: European Medicines Agency (EMA) (2021) Wegovy