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Acquired MET Y1248H and D1246N mutations mediate resistance to MET inhibitors in non-small cell lung cancer

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(2012) demonstrated that long-term exposure to CP impaired autophagy leading to CP resistance, and interestingly, upregulation of autophagic response under such condition re-sensitized resistant cells to CP-induced cell death

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Mild side effects, such as nausea, skin bumps, and itching, as well as comedonal acne and epigastric pain were experienced by nine percent of the glutathione supplement group and eight percent of the placebo group during the first four weeks