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The absence of randomized controlled trials means long-term organ impact, hormonal effects, and contraindications remain undocumented

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In an open label, single arm and multi-center pilot study, 34 Japanese patients diagnosed with NAFLD (but without hepatic decompensation), with ultrasound, were prospectively evaluated over the course of 7 months

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43 , D447D452 (2015)

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But it establishes a precedent

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Short-chain fatty acids stimulate glucagon-like peptide-1 secretion via the G-protein-coupled receptor FFAR2 Diabetes 2012;61(2):364-371 doi:10.2337/db11-1019

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