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2.2.5.2 Prebiotics Prebiotics could be helpful in the management of PD, even if only limited studies have been done on human PD patients to find out how prebiotic supplementation affects them (Table 5)

The International Society of Sports Nutrition suggests creatine may be acceptable for younger athletes only in specific cases, such as those engaged in serious, supervised competitive training, eating a balanced diet, understanding proper use, and not exceeding recommended doses

However, both substances independently affect blood glucose regulation and gastrointestinal function, creating physiological risks that require clinical consideration

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