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Therefore, these findings further support the observation that low IGF-1 preferentially benefits females, and suggest that a potentially broad therapeutic window to target IGF-1R signaling may exist in females, with greater benefit possible by initiating at even younger ages than implemented in this study

However, weight loss averages 46% at 14 mg, significantly lower than seen with newer trials

What if I have excess skin after the weight loss

They allow prescribers and patients to have careful discussions