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Hypoglycaemia (low blood sugar levels) GLP-1 RAs are glucose-dependent stimulators of insulin, meaning they shouldnt cause dangerous hypoglycemia on their own in a healthy person (unlike taking insulin)

Split Dosing Option Some protocols call for splitting the daily dose into two administrations, typically morning and evening

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doi: 10.1097/WCO.0000000000000094

Buyers with kidney disease should also consult a healthcare provider, since the kidneys are the primary site where L-Citrulline is converted to L-Arginine, and impaired renal function can affect amino acid processing in ways that aren't fully predictable from published research