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While Savoy-HCG is generally safe, some patients may experience mild side effects such as headache, mood changes, injection site pain, or abdominal discomfort

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In cases of severe deficiency, a course of injections may be given over several weeks before transitioning to maintenance treatment

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The SURPASS-CVOT and retatrutide Phase 3 cardiovascular trials will generate the datasets that establish whether the dual- and triple-agonist compounds replicate the CV-outcome signal semaglutide produced, exceed it, or diverge from it