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Investigation into ARCI as a treatable condition is relevant to a wide range of cognitive impairment conditions, since mild age-related neuropathology increases risk for more severe neuropathology associated with MCI and dementia associated with Alzheimers Disease [5]

Its action in addictive disorders is currently under investigation (45)

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doi: 10.1017/S0007114511004934 15 ChakrabortyAGuhaSChakrabortyD

Antioxidant-superoxide dismutase interactions The interaction between plant antioxidants (flavonoids), the antioxidant enzyme SOD, and inflammatory enzymes such as nitric oxide synthase and cyclooxygenase-2 (COX-2) has been shown to prevent inflammation