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GSH is a cysteine-containing tripeptide that can be broken down by GGT enzymes into cysteinylglycine and glutamate

This is the patient group in which the STEP-HFpEF, STEP-HFpEF DM and SUMMIT trials demonstrated robust benefits

Intermittent fasting dissociates beneficial effects of dietary restriction on glucose metabolism and neuronal resistance to injury from calorie intake

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In addition, a recent in silico molecular docking study regarding the DPP4/CTNNB1/MET signatures showed that stagliptin could be a potential TC drug, however more investigations are surely needed to confirm it ( Gemigliptin Gemigliptin is an orally bioavailable inhibitor of DPP-4, with hypoglycemic and potential renoprotective activities