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Pfizer presented results from the first 28 weeks of its ongoing middle-stage trial on the drug at the American Diabetes Associations annual conference on Saturday

Wilson SH, Simari RD, Best PJ, Peterson TE, Lerman LO, Aviram M, Nath KA, Holmes DR, Lerman A: Simvastatin preserves coronary endothelial function in hypercholesterolemia in the absence of lipid lowering

PTEN deficiency mediates a reciprocal response to IGFI and mTOR inhibition

Below, linkers employing these various release strategies will be discussed for each cytotoxin class since the few linker-drug motifs that have been successful have repeatedly been used for other antibodies