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Research published in obesity journals indicates that people who taper gradually maintain more weight loss than those who quit cold turkey, even when final weight outcomes appear similar initially

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10.5897/JMPR12.1221 14 BarbagalloI.VanellaL.DistefanoA.NicolosiD.MaravignaA.LazzarinoG.et al (2016)

Conclusion As the multi-hit hypothesis holds, combining the therapeutic approaches of GLP-1 agonists with resmetirom seems like a promising strategy by targeting the multifaceted pathophysiology of MASH, which may lead to improved patient outcomes

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