A 10 mg vial with 2 mL: each 5 units equals 250 mcg
Current consensus is that GLP-1 treatment benefits outweigh the risk of EWDR: the drugs reduce the risk of further microvascular damage from poor glycemic control and reduce the chance of death from cardiovascular disease, while the impact on DR is short-lived and can be treated
Linagliptin is the exception, with 10,000 patients, exposed for up to 2 years) of the sitagliptin and vildagliptin clinical trials have been published, showing no increased risk for urinary tract or respiratory infections or headache (and indeed, no increased risk of any other adverse effect) with the DPP-4 inhibitors compared to placebo or comparator [95,96]
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