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promotes SESN2 expression, which strengthens antioxidant capacity via the Nrf2/Keap1 pathway, boosts autophagy, and improves insulin sensitivitykey mechanisms for mitigating NAFLD

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474 T2DM patients treated with either exenatide, semaglutide, or liraglutide experienced obvious benefits in decreasing hepatic lipid levels and the levels of inflammatory markers, which improved HbA1c levels and decreased body weight

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"MOTS-c can significantly enhance physical performance in young, middle-age, and old mice." Reynolds et al., Nature Communications , 2021 [3] The ceiling on all of this is the same ceiling every mitochondrial peptide hits: the outcome data is rodent data