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Beyond mechanical load, adipose tissue secretes inflammatory cytokines like IL-6, TNF-alpha, and leptin that accelerate cartilage degradation and amplify joint pain

About this article Once-Weekly Semaglutide in Adults with Overweight or Obesity The New England Journal of Medicine (NEJM) (Mar 2021) Clinical Recommendations for the Management of Adverse Events Associated with Glucagon-Like Peptide-1 Receptor Agonists Journal of Clinical Medicine (Dec 2022) Notes:Article published