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Among gut-derived uremic toxins, indoxyl sulfate and p-cresyl sulfate are largely protein bound in the blood circulation (mostly to albumin) and thus poorly cleared by diffusive dialysis procedures (75)

Potassium, iron, magnesium, and manganese are also present in smaller amounts, and participate in blood formation, neurotransmission, and bone health, among other functions

Not only are people more likely to be confident in the recommendations coming from their doctors, but doctors find themselves better prepared to help patients who have failed on current therapeutic approaches

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Current Opinion in Endocrine and Metabolic Research, 16, 1927