Subscribe to Healthy Balance Get timely health and wellness tips from UVA Health experts
It should be a gentle cascade
Internationally, Lilly holds an estimated market share above 53% across more than 55 launched countries, per Patrik Jonsson, President of Lilly International, on the earnings call
If yours does not, supplementation or regular B12 injections are worth discussing with your provider
Retatrutide Advantages Highest weight loss ever reported in an obesity drug trial Third receptor adds energy expenditure and fat oxidation Weight loss curve not yet plateaued at 48 weeks Stronger liver fat reduction potential via glucagon pathway 100% of highest-dose participants lost at least 5% body weight Tirzepatide Advantages FDA approved and commercially available (Mounjaro, Zepbound) Large Phase 3 dataset with 10,000+ participants across programs No dose-dependent heart rate increase observed Longer real-world data and post-marketing surveillance Multiple completed trials across obesity and diabetes indications Key Takeaways Retatrutides Phase 2 data shows a small numerical weight loss advantage over tirzepatides Phase 3 data (24.2% vs 22.5%), but the comparison is indirect and the trial designs are not equivalent
Tap water, purified drinking water, or distilled water without preservatives should never be used
