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Phosphorylation of p70S6-K increases translation of ribosomal and other mRNAs containing a 5 tract of oligopyrimidines

Int J Radiat Oncol Biol Phys 96(2S):S105, 2016

Mutations in the selenocysteine insertion sequence-binding protein 2 gene lead to a multisystem selenoprotein deficiency disorder in humans

While B12 is generally safe, caution is needed in specific clinical situations: Lebers Disease (Hereditary Optic Neuropathy): B12 injections are generally contraindicated or should be used with extreme caution, as they may potentially aggravate optic atrophy in this rare condition

In: Goldman L, Schafer A, eds

Drugs can reduce appetite and alter metabolism, leading to nutrient deficiencies