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Almost all efficacy data come from a single research group, and independent replication of the larger-effect-size studies remains limited
Aliquots (500 L) of blood collected with ethylenediamine tetraacetic acid (EDTA) 5% were analyzed using an automatic hematologic analyzer ( Hematoclin 2.8 VET, Starlab, Salvador, BA, BRA) and blood samples (1000 L) collected without anticoagulant were used to obtain serum for analyses of oxidative stress (12 and 24 h post CLP) and cytokines (24 h post CLP)
This significantly enhanced the accumulation of cisplatin in tumor cells, increasing efficacy in cisplatin resistant cells and decreased tossicity 95
This article explains the benefits and mechanisms of action of using these two medications together
As more research and controlled trials become available, we will better understand how to optimize GHK-Cu treatment identifying the best doses, patient types, and protocols