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This can lead to an imbalance in the redox potential, export of GSSG and eventual depletion of GSH, a classical state of oxidative stress [26] observed in a number of diseases including inflammation [27], autoimmune disorders [28,29] and liver disorders [30]

Redox-sensitive GFP in Arabidopsis thaliana is a quantitative biosensor for the redox potential of the cellular glutathione redox buffer

1981, in Effect of tryptophan administration on tryptophan, 5-hydroxyindoleacetic acid, and indoleacetic acid in human lumbar and cisternal cerebrospinal fluid. Supplementing with tryptophan helps support serotonin synthesis, especially when dietary intake is insufficient

K.OKeeffeG.SchrettlM.KavanaghK.et al (2012)