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Age-related decline in NAD+ can cause low energy and poor cognition

Another mechanism linking obesity and IR is chronic inflammatory responses, including increased production and release of pro-inflammatory factors such as TNF-, IL-6, and C-reactive protein, which cause insulin resistance in liver, skeletal muscle, and adipose tissue through insulin-interfering signaling pathways (102)

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A healthy diet that includes fresh fruits, vegetables, whole grains, lean meats, and low-fat dairy can support weight loss and heart health

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