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Abstract Interleukin-23 (IL-23) and Tumor Necrosis Factor-alpha (TNF-) are key pro-inflammatory cytokines that regulate the progression of inflammation

Endocrinology Targeting the central melanocortin system for the treatment of metabolic disorders 2023 DOI: 10.1038/s41574-023-00855-y PMID: 37365323 Sweeney P, Gimenez LE, Hernandez CC, et al

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This tends to become apparent within 1-2 weeks , as patients feel less fatigued and experience greater physical endurance

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