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Is Retatrutide safe for long-term use

International Journal of Pharmaceutics, 447 , 75-93

Hydroquinone (HQ), another well-studied whitening agent, has been used clinically in leading cosmetic hyperpigmentation treatment 23 , however, it was also found to cause serious problems by generating reactive oxygen species leading to oxidative damage of lipids and permanent loss of melanocytes

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The second, more sustained phase occurs when nutrients directly contact L-cells in the lower small intestine and colon, producing a more prolonged GLP-1 release that continues for several hours after a meal

Perlman, R