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Front Pharmacol 12:670479 Attachaipanich T, Chattipakorn SC, Chattipakorn N (2023) Potential roles of melatonin in doxorubicin-induced cardiotoxicity: from cellular mechanisms to clinical application

8226/S, 8226/S-CR, and 8226/S-ATOR05 cells were treated with the indicated concentrations of ATO, DAR, Mel, Bz, ABT-737 or Dox for 24 h and apoptosis was assessed by flow cytometry and graphed as percent of control Annexin V positive cells vs

Reconstitute it with a fixed volume of bacteriostatic water so the concentration lands where the protocol expects

Vitamin C is also a potent anti oxidant, that along with GSH compete for removal of free radicals in the cell

But theres a pattern to who tends to seek it out and who may be a reasonable candidate after a proper evaluation