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Patients with pre-existing migraines, poor fluid intake, or polycystic ovary syndrome may report higher headache frequency during dose initiation

Importance of Whole Foods: Natural foods deliver nutrients in a complex biochemical context that enhances their absorption and effectiveness

In practice, the optimal dose schedule likely varies by body weight, metabolic baseline, genetic factors, and individual receptor sensitivity

Weight reduction itself often correlates with decreased migraine frequency, particularly in obese populations where weight-related metabolic stress compounds headache triggers

One way of achieving fascicular selectivity is by placing a multi-contact cuff electrode around the cervical vagus nerve (cVN)

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