Likely secondary to increased NAD+-dependent mitochondrial activity
While empirical research on AOD-9604 is in early stages, there have been almost no reported side effects, and the treatment has no downtime
It never has been, and it is unlikely to be, because FDA approval requires hundreds of millions of dollars in clinical trial investment that no compounding pharmacy can justify for a generic combination
Researchers are exploring its potential in metabolic health, longevity, and other cellular processes in 2026
Use of corticosteroids, depending on the dose, duration, and specified steroid, may result in inhibition of endogenous steroid production following drug withdrawal.
If needed for a clear medical indication (such as treating pellagra in a pregnant patient), niacinamide can be used with caution, but unnecessary high-dose B supplementation is avoided in pregnancy