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7: 5749 Giugliano D, Ceriello A, Paolisso G

F., Karamsadkar, S

National Natural Science Foundation of China (Grant numbers 72574038)

Under the coordinated catalysis of bile acid-CoA ligase (BAL) and bile acid acyl CoA: amino acid N-acyltransferase (BAT), these primary bile acids can undergo conjugation reaction with taurine to generate taurine-conjugated bile acids (Tau-BAs), mainly including taurocholic acid (TCA) and taurochenodeoxycholic acid (TCDCA), which become important components of primary bile acids