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The genes responsible for regulating lipid and glucose homeostasis are controlled by chemerin, a highly expressed chemokine in the liver and white adipose tissue

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Notably, EA produced a more pronounced reduction in liver enzymes and triglycerides, suggesting that its effects may be mediated by both anti-inflammatory and metabolic pathways (87)

1, 2, 3, 4 These drugs appear to be generally safe, however, a concern receiving increasing attention is the development of pancreatitis

Starting dose, titration speed, and food timing dramatically affect tolerability independent of medication type