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doi:10.1016/0361-9230(86)90111-5 Scherschlicht R, Aeppli L, Polc P, Haefely W

Through the analysis of numerous in vivo and in vitro studies aimed at determining the mechanisms by which GLP-1 enhances insulin secretion in individuals with normal glucose tolerance or T2DM, two main intracellular mechanisms underlying the incretin effect have emerged

Some users find they become more sensitive to caffeine as their sleep improves, noticing disruption from amounts they previously tolerated

Weight loss effects comparable to prescription GLP-1 medications are not substantiated by supplement research