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Ban K, Noyan-Ashraf MH, Hoefer J, Bolz -S-S, Drucker DJ, Husain M

GLP-1 as Part of Your Metabolic Optimization Stack While GLP-1 is a powerful tool, it works best as part of an integrated metabolic optimization plan

Jama 316 (5), 500508

17 West, S., et al

The percentage of participants who had weight reduction of 5% or more was 85%, 89%, and 91% with 5 mg, 10 mg, and 15 mg of tirzepatide, respectively, and 35% with placebo

However, the data also shows that once older adults are already engaged with GLP-1 treatment, resistance to tablets drops sharply: 43.19% say pills are more appealing than injections 64.94% of injectable users would consider switching This indicates the primary barrier among older adults may not be the pill format itself, but rather initial adoption of GLP-1 treatment in general