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The capacity of baicalein to increase the expression of cyclooxygenase-2 (COX-2), which is generally downregulated during adipogenesis, may explain its anti-adipogenic activity (Cha et al., 2006)

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[16] If gastrointestinal side effects remain troublesome despite supportive measures, your healthcare team may consider alternative GLP-1 receptor agonists or other glucose-lowering therapies