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doi:10.1016/j.eclinm.2024.102789 14

We now better understand that weight regulation involves: hormones insulin resistance stress sleep genetics metabolism medications emotional health lifestyle patterns This is exactly why compassionate, medically supervised care matters

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Further research investigating time-course changes in citrulline concentration following CM supplementation is required to determine the optimal strategy, although the best recommendation at the moment would be 1 h prior to exercise

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However, it is especially remarkable that within the SUMMIT trial, among patients with HFpEF, the dual glucagon-like peptide-1/glucose-dependent insulinotropic polypeptide agonist, tirzepatide, significantly reduces the combined risk of cardiovascular death or the exacerbation of HF