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An early clinical trial in 13 patients with type 2 diabetes found that a single intravenous infusion of 1,000 mg of lipoic acid improved insulin-stimulated glucose disposal (i.e., insulin sensitivity) by 50% compared to a placebo infusion (57)

This is not a failure of willpower but rather a predictable biological response to the removal of pharmacological intervention

Antioxidants act like sponges, soaking up free radicals

For example, insufficient production of the protective compound butyrate reduces its anti-inflammatory and anti-fibrotic effects by inhibiting NF-B pathway [89]

Clinical Medical Research Studies 2, 113

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