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Introduction Understanding the evolution of the gut microbiota and its internal and external impacts on the intestine, as well as the risk factors for cardiovascular diseases (CVDs), such as metabolic syndrome, has attracted a great deal of attention (1, 2)

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Smoking Nicotine increases oxidative stress and reduces glutathione levels in cells, weakening its therapeutic effect

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Kidney function, as assessed with eGFR (estimated glomerular filtration rate), was calculated with the IDMS traceable MDRD-study equation

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The frequency of use will depend on the advice of your healthcare provider

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