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A large proportion of patients Holst found himself operating on during this period had duodenal ulcers, a disorder increasingly common in Western communities from the 1950s (Pesheva)

GLP-1s help to stimulate insulin release and reduce glucagon production

Coggon D, Reading I, Croft P, McLaren M, Barrett D, Cooper C (2001) Knee osteoarthritis and obesity

If you experience persistent difficulties with blood sugar control, unexplained weight gain, or uncontrolled appetite despite appropriate lifestyle measures, consultation with a primary care physician or endocrinologist is warranted

This multi-factor concept may explain the difficulty in achieving and maintaining glycemic goals with traditional therapies

(2025, July 29)