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In ErbB2-transformed MCF10A cells, there is increased expression of GLS mRNA and protein compared to MCF-10A cells, and knockdown of ErbB2 leads to downregulation of GLS expression [103]

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We constrained our review to five general areas of research in which measurement or manipulations of the glutamatergic system in groups of schizophrenia patients have been implemented: neuro-imaging (PET and 1 H-MRS), CSF and peripheral blood, post-mortem, genetics, and clinical trials