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Negative side effects occur rarely and include a decrease in energy levels (which happens in about 2-3% of my patients)

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Safety and tolerability of intravenous BPC157 in humans

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Such channel modifications alter ion flow, transmembrane potential, and reduce both APD and conduction velocity, ultimately disrupting cardiac electrophysiological activity and elevating the risk of arrhythmias ( The HCN channel, also known as the If channel, is activated near the end of the repolarization phase, enabling inward currents mediated by Na + and K + throughout diastolic depolarization (Rivolta et al., 2020)