In summary, through the integration of rigorous clinical trial design and deep mechanistic understanding, bile-based TCMs can be transformed into safe, evidence-based, and highly effective treatments that address the growing global burden of chronic liver diseases
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However, if the solid is filtered out or removed by centrifugation, the remaining supernatant retains its high soluble form, unless heterogeneous nucleation might trigger the monohydrate
doi: 10.1093/annonc/mds654
Trial Registration ClinicalTrials.gov Identifier: NCT04660643 Introduction Obesity is a chronic disease associated with elevated risk for cardiometabolic complications