OTHER BRANDS Opaque appearance indicates large particle solution
Glutathione (GSH) is the most abundant antioxidant in the body 6 and one of the most concentrated metabolites in the cell 7
Furthermore, GST fusion proteins are susceptible to TG2-mediated aggregation, independent of the specific fused protein that is used
Then, -GC is combined with Gly through a typical -linkage by the enzyme GSH synthetase (GS), which also requires ATP and Mg 2+ as co-substrates, ultimately resulting in the formation of GSH (Figure 2A) [11]
Redox control of glutamine utilization in cancer
If these observations, may be correlated with the efflux of this drug by the multidrug transporters, directly or indirectly, and in particular by MDR1, remains to be established