In one published case, an active, lean-adjacent man lost about one-third of his total weight as muscle on 2.5 mg and recovered it after adding resistance training and increasing protein. This is a cautionary case, not an incidence estimate
Stagg AJ, Smith MA, Malyszko J, et al
Additionally, like all health-related content on this website, this review was thoroughly vetted by one or more members of our Medical Review Board for accuracy
Studies show a connection between insomnia and levels of B12, while other studies show that high levels of B12 can lead to increased sleep disruptions and a shorter sleep duration 6, 7
These physical changes are the result of sustained, optimized growth hormone levels
1, Supplementary Tables 1 and 2)