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In addition, Reelin is an extracellular matrix glycoprotein closely related to neural development, which is involved in the regulation of neuronal migration, synaptic plasticity and neural network formation (36).Reelin affects the migration and synaptic integration of GABAergic interneurons by regulating disabled-1 (Dab1) and PI3K/AKT pathways

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The second reason is a steadily decreasing amount of polyunsaturated fatty acids

Ablation of the inflammatory enzyme myeloperoxidase mitigates features of Parkinson's disease in mice