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Natural GLP-1 is produced by the body, however, as we discussed earlier, it has a very short lifespan, and patients with T2D and other metabolic disorders can experience reduced secretion of the hormone or reduced sensitivity to it

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Despite FLOW and REMODEL not including kidney transplant recipients, it will undoubtedly drive interest in preclinical mechanistic studies elucidating the role of GLP-1RAs in the kidney

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