Individuals with T2DM and obesity face an elevated risk of various comorbidities, including a fivefold increase in end-stage renal disease, a heightened risk of obesity-related cancers, and a 64% higher likelihood of diabetic retinopathy
Inhibition of tumor growth and elimination of multiple metastases in human prostate and breast xenografts by systemic inoculation of a host defense-like lytic peptide
Most weight-loss-related hair shedding traces directly back to nutritional inadequacy
doi: 10.4067/s0716-10182022000200248 32 WheatL
*Correspondence: Hanlin Zeng, [email protected] This article was submitted to Skin Cancer, a section of the journal Frontiers in Oncology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
Conclusions and future perspective Despite a large part of literature exploring on the accumulation and the origin of ROS, current antioxidant-based therapies lack of specificity for dysfunctional tissues, cells, and organelles, and thus may not reach an effective concentration at the target site of pathologic oxidative stress
