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Further mechanistic studies have found that treatment with TMZ promoted cardiac Nrf2 expression, indicating that TMZ enhanced the clearance of oxidative stress by activating the GSH system through the Nrf2 signaling pathway [210]

The Honest Truth breaks down the role of absorption

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It is intriguing that mercury and antibiotic resistance genes can be localized in micro-organisms isolated from individual slices of a stratified core sample of sphagnum, a deposit of since-undisturbed decayed plant organic matter dating back 2000 years [88]

A second mechanism is based on the competitive inhibition of the GSSG binding site by G-S-G and by the metal glutathione conjugate, as depicted in Scheme 11

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